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Topic: Piggies really are quasi-primates (Read 182 times) previous topic - next topic

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Piggies really are quasi-primates

A few years back, I claimed that my own research showed that pigs were unlike their artiodactylan cousins and more like primates. I was riducled on this very site for making such a bold claim.  I am pleased to my scientific peers have confirmed my findings.

https://phys.org/news/2015-09-hidden-evolutionary-relationship-pigs-primates.html
http://www.biorxiv.org/content/biorxiv/early/2015/08/31/025791.full.pdf

Quote
We  identified  and  characterized  a  free  PRE-1  element  inserted  into  the  promoter  region  of  the 
porcine  IGFBP7 gene  whose  integration  mechanisms  into  the  genome,  including  copy  number, 
distribution  preferences,  capacity  to  exonize  and  phyloclustering  pattern  are  similar  to  that  of  the 
primate  Alu  element.  98%  of  these  PRE-1  elements  also  contain  two  conserved  internal  AluI 
restriction enzyme recognition sites, and the RNA structure of PRE1 can be folded into a two arms
model like the Alu RNA structure. It is more surprising that the length of the PRE-1 fragments is
nearly  the  same  in  20  chromosomes  and  positively  correlated  to  its  fracture  site  frequency.  All  of 
these  fracture  sites  are  close  to  the  mutation  hot  spots  of  PRE-1  families,  and  most  of  these 
hot  spots  are  located  in  the  non-complementary  fragile  regions  of  the  PRE-1  RNA  structure. 
Sequence   homology   analysis   showed   that   the   PRE-1   element   seemed   to   share   a   common  
ancestor  7SL  RNA  with  primates  but  was  generated  by  different  evolutionary  model,  which 
suggests that the suidae may be the closest relatives to primates in laurasiatheria.

https://www.mnn.com/earth-matters/animals/stories/pigs-and-humans-more-closely-related-thought-according-genetic-analysis
The upshot of all of this, according to the study's author, is that the suidae family (that is, the swine family) could conceivably be grouped into a family that is otherwise mostly inhabited by primates, at least in terms of 7SL RNA-derived SINEs.

  • Faid
Re: Piggies really are quasi-primates
Reply #1
Dammit clasite! You let people here intimidate you into being insecure about your findings and not publishing them. Now someone else will get all the bucks and glory and martinis and bjs from hot post-grads.

Believe in yourself man. You'll make it next time.
Who even made the rule that we cannot group ducks and fish together for the simple reason that they are both aquatic? If I want to group them that way and it serves my purpose then I can jolly well do it however I want to and it is still a nested hierarchy and you can't tell me that it's not.

Re: Piggies really are quasi-primates
Reply #2


The evolutionists insist on monophyly.  The data suggest polyphyly.

Re: Piggies really are quasi-primates
Reply #3
https://phys.org/news/2015-09-hidden-evolutionary-relationship-pigs-primates.html
http://www.biorxiv.org/content/biorxiv/early/2015/08/31/025791.full.pdf

Quote
We  identified  and  characterized  a  free  PRE-1  element  inserted  into  the  promoter  region  of  the 
porcine  IGFBP7 gene  whose  integration  mechanisms  into  the  genome,  including  copy  number, 
distribution  preferences,  capacity  to  exonize  and  phyloclustering  pattern  are  similar  to  that  of  the 
primate  Alu  element.  98%  of  these  PRE-1  elements  also  contain  two  conserved  internal  AluI 
restriction enzyme recognition sites, and the RNA structure of PRE1 can be folded into a two arms
model like the Alu RNA structure. It is more surprising that the length of the PRE-1 fragments is
nearly  the  same  in  20  chromosomes  and  positively  correlated  to  its  fracture  site  frequency.  All  of 
these  fracture  sites  are  close  to  the  mutation  hot  spots  of  PRE-1  families,  and  most  of  these 
hot  spots  are  located  in  the  non-complementary  fragile  regions  of  the  PRE-1  RNA  structure. 
Sequence  homology  analysis  showed  that  the  PRE-1  element  seemed  to  share  a  common 
ancestor  7SL  RNA  with  primates  but  was  generated  by  different  evolutionary  model,  which 
suggests that the suidae may be the closest relatives to primates in laurasiatheria.
::)
Last two words are important.    Still a long way from laurasiatheria to primates.


An alternate hypothesis is that 7SL RNA evolved earlier than was previously thought and can be found outside of primates by structural conservation, rather than sequence conservation.   Would need to examine the genomes of more organisms in the tree to determine whether these evolved 7SL RNAs exist.  Probably harder than you think as assembling repeat sequences is a huge pain in the ass.  

Anyway, its 2017, Joe.  You don't need to propose nonsense like polyphyly as a rationalization for why you find farm animals so goddamned sexy.  Let your freak flag fly!


  • Last Edit: July 10, 2017, 04:36:40 PM by entropy
While you were getting your PhD in virology, I got my PhD in truth detection. :wave:  Dave Hawkins

Re: Piggies really are quasi-primates
Reply #4
This is the thread from old TR if anyone wants a walk down memory lane:

Part 1:  http://talkrational.org/archive/showthread.php?t=21799
Part 2: http://talkrational.org/archive/showthread.php?t=22217

ETA:  Lol.  http://talkrational.org/archive/showthread.php?p=768259#post768259

ETA2:  Forgot this was from the same thread http://talkrational.org/archive/showthread.php?p=777499#post777499   I miss the old Joe...
  • Last Edit: July 10, 2017, 05:38:56 PM by entropy
While you were getting your PhD in virology, I got my PhD in truth detection. :wave:  Dave Hawkins

Re: Piggies really are quasi-primates
Reply #5
Anyway, its 2017, Joe.  You don't need to propose nonsense like polyphyly as a rationalization for why you find farm animals so goddamned sexy.  Let your freak flag fly!

I see no reason why pigs could be a special case...a hybid between cows and monkeys.



Re: Piggies really are quasi-primates
Reply #6
its u. ur the hybrid

Re: Piggies really are quasi-primates
Reply #7
this is why preprints are dumb. this is probably evidence for HGT, likely viral-mediated. It's not evidence for much else. Certainly not bizarre phylogenetic rearrangements.

Re: Piggies really are quasi-primates
Reply #8
Anyway, its 2017, Joe.  You don't need to propose nonsense like polyphyly as a rationalization for why you find farm animals so goddamned sexy.  Let your freak flag fly!
I see no reason why pigs could be a special case...a hybid between cows and monkeys.

Googled hybid. Does not seem to be a biological term, but a riding school

http://hybidfarm.com/hybid-programs/

No piggies there Joe. Just some human apes and Equus caballus.


Believer in High Powers, and naturally, logarithms.
Pikkiwoki is the one true god.

Re: Piggies really are quasi-primates
Reply #9
What happened to you Joe?  You used to be cool... :(  I haven't had a good Nemesis in years...  Now I just go in and work my nine to five in a well funded Ivy League lab and remember the good old days...
  • Last Edit: July 14, 2017, 07:37:34 PM by entropy
While you were getting your PhD in virology, I got my PhD in truth detection. :wave:  Dave Hawkins