Skip to main content

TR Memescape

  • Talk Rational: Believe in Dawkins? We can fix that.

Show Posts

This section allows you to view all posts made by this member. Note that you can only see posts made in areas you currently have access to.

Messages - meepmeep

2201
Well...

Quote
The latest report, published in October 2016, shows that sales of antibiotics for use in animals in Europe fell by 2.4% between 2011 and 2014, despite a considerable increase in a Member State which switched to an improved data collection system in 2014 and registered more sales. In 24 of those countries that provided data for this period, sales fell by 12%:

http://www.ema.europa.eu/docs/en_GB/document_library/Report/2016/10/WC500214217.pdf

Quote
In total, 25 countries have provided data for all the years between 2011 to 2014. A fall in sales (in mg/PCU) of more than 5 % was observed in 10 of these countries, whilst there was an increase of more than 5 % in five countries during the reference period (Table 8 ). The PCU was stable across the years, with only a 0.9 % reduction in the total PCU of the 25 countries, and there was also an overall reduction of 2.9 % in the volume of tonnes sold.

For 25 countries reporting sales data to ESVAC for the years 2011-2014, an overall fall in sales (mg/PCU) of 2.4% was observed. The sales were 162 mg/PCU, 153 mg/PCU, 147 mg/PCU and 158 mg/PCU in 2011, 2012, 2013 and 2014, respectively (Figure 56).

Spain changed its system for collecting sales data in 2014, and there were indications that some of the highest selling VMPs for 2014 had not been reported by MAHs between 2011-2013, despite being marketed during this period. Therefore, the suggestion is that the sales data for Spain for 2011 to 2013 represent substantial underestimates. The consumption of antimicrobials in Spain is one of the highest among the European countries participating in ESVAC; sales aggregated by the 25 countries, e.g. 2011 and 2014, are thus not directly comparable.

By excluding Spain, an overall fall in sales (mg/PCU) of 12 % from 2011 to 2014 (from 138 mg/PCU in 2011 to 121  mg/PCU in 2014) was observed in the remaining 24 countries (Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Hungary, Iceland, Italy, Ireland, Latvia, Lithuania, the Netherlands, Norway, Poland, Portugal, Slovakia, Slovenia, Sweden and the United Kingdom).

Some things to consider:
Quote
For example, the dose for a whole treatment (DCDvet) with an oral fluoroquinolone VMP may be 10-40 mg/kg between  cattle, pigs and poultry, while with an oral tetracycline VMP this may vary between 110 and 280 mg/kg. This implies that a given weight of active ingredient of fluoroquinolone sold can be used to treat several times as many animals as the same weight of active ingredient of a tetracycline. Furthermore, within an antimicrobial class there may be different dosages for different substances; for example, the dosage of doxycycline is about one-quarter of the dosage of oxytetracycline. Another consideration is that the treatment dosage may differ significantly according to species; for fish, a typical tetracycline dosage for the whole treatment is 800 mg/kg, or some six times higher than that for terrestrial animals. The data in this report cover all food-producing animals together, and therefore it was not possible to take into account differences in dosing when reporting the data. Since the sales patterns and the animal demographics vary substantially between countries, comparison of the sales data across the countries should be done with great care.

Quote
The PCU was stable over the years; only a 0.9 % reduction of PCU was observed for the 25 countries, while the reduction in tonnes sold was 2.9 %. In 25 countries reporting sales data to ESVAC for the years 2011-2014, there was an overall decrease in the sales (mg/PCU) of 2.4 %. The sales were 162 mg/PCU, 153 mg/PCU, 147 mg/PCU and 158 mg/PCU in 2011, 2012, 2013 and 2014, respectively (Figure 56).

However, Spain changed its system for collecting data in 2014 data, when it was identified that for certain MAHs, sales of some VMPs identified as high-selling (tonnes) VMPs in 2014 had not been reported for some MAHs for the previous years (2011-2013), although they were marketed during these years. Therefore, the suggestion is that the sales data for Spain for 2011 to 2013 represent substantial underestimates. The consumption of antimicrobials in Spain is one of the highest among the European countries participating in the ESVAC; sales aggregated by the 25 countries for 2011 and 2014, for example, are therefore not directly comparable.

By excluding Spain, a 12 % fall in the sales (mg/PCU) was observed between 2011 (138 mg/PCU) and 2014 (121 mg/PCU) in the remaining 24 countries (Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Hungary, Iceland, Italy, Ireland, Latvia, Lithuania, the Netherlands, Norway, Poland, Portugal, Slovakia, Slovenia, Sweden and the United Kingdom).

The sales (mg/PCU) of 3rd- and 4th-generation cephalosporins in 25 countries, that provided data for the years 2011-2014, remained stable during this period, while an increase of 18% was observed for the fluoroquinolones (Figure 56.). The sales (mg/PCU) of polymyxins (mostly colistin) in these 25 countries decreased by 9 %.

From 2011 to 2014, a drop of more than 5 % (range 8 % to 40 %) in the sales (mg/PCU) was observed for nine countries (Table 8.). For five countries, an increase of more than 5 % was observed (range 11 % to 51 %). The country with an increase in sales of 51 % changed its data collection system between 2011 and 2014, consequently these data should be interpreted with a great care.

Quote
A large difference in the sales, expressed as mg/PCU, was observed between the most- and least-selling countries. This is likely to be partly due to differences in the composition of the animal population in the various countries (e.g. more pigs than cattle). Furthermore, differences in the production system may play an important role. Amongst other factors, there is also considerable variation in terms of daily dosage and length of treatment between the various antimicrobial agents and formulations used, and other factors must also be considered. Differences in the selection of data source -- i.e. prescriptions, sales data or purchase data -- may have an impact, although this is considered to be low.

In 2014, the prescribing patterns for the various veterinary antimicrobial classes, expressed as mg/PCU, varied substantially between the countries. Notable variations were observed between the different countries in the proportion of the sales accounted for by the CIAs with the highest priority in human medicine -- 3rd- and 4th-generation cephalosporins, fluoroquinolones and macrolides, with proportions ranging from 0.01% to 1.5%, 0.01% to11.9%, and 0% to 16.9 %, respectively. Since the major proportion of the sales of these classes/subclasses was accounted for by macrolides, the variations observed between the countries are likely, in part, to reflect difference in the relative proportion of the various animal species and, in particular, differences in pig production (use of macrolides).

Overall, in the 29 countries, the sales (mg/PCU) of 3rd- and 4th-generation cephalosporins, fluoroquinolones, polymyxins (mostly colistin) and macrolides accounted for 0.2 %, 1.9 %, 6.6 % and 7.5 %, respectively, of the total sales of antimicrobial VMPs in 2014.

How about we deny access to antibiotics for the farmers, vets, and manufacturers.

Don't be a dumbass.
2203
at this point he's gone full nazi. You can almost see the ((())) in his speech.

I doubt he or anyone else thinks that your average person gives a fuck about Sidney Blumenthal. ANd you could almost hear the fucking ((( ))) every time he ominously said Sidney Blumenthal.

Nobody reads my posts.  :sadcheer:
2204
NYT responds: http://documents.latimes.com/read-new-york-times-response-donald-trumps-lawyers/

:burnsauce:

Trump's response to the People magazine accusation: "I didn't do it. I mean, look at her!"

Also Michelle Obama's speech was really something. I usually skip over this kind of shit, but this one is worth listening to: https://www.rawstory.com/2016/10/watch-choking-back-tears-michelle-obama-delivers-powerful-speech-on-trumps-abuse-of-women/
2205
I remember seeing a western journalist interview zhirinovsky about 15 years ago.  he softened his russian fascist rhetoric a little and said america and russia didn't have to remain enemies forever; and in time maybe they could help us with our blacks and other problems.

Is this before or after Russia takes back Alaska and exiles all the Ukrainians there?
2206
Getting annoyed by people freaking the fuck out about Russia. There have been two stories going around, and they're all getting tied into "and that's why we need TRUMP!".

(1) Russia told its citizens to come back to the motherland IMMEDIATELY and to pull their children from school IMMEDIATELY because NUCLEAR WAR IS IMMINENT!!!!! :stopper:

Some minor media outlet reported that government deputies and administrative staff abroad got a message from the office of the president recommending that they take their children out of Western universities and have them go to school in Russia. And they recommended that any other family members living abroad with them who are still Russian citizens should also return. The explanation was that it looks bad for politicians to go on TV and blather on about patriotism and how the West is against Russia all while having their children educated at elite Western schools. And there have been some scandals involving high-ranking politicians criticizing the West while their kids are at European and American universities. Lavrov's daughter, who was going to school in the US, was criticized for speaking Russian with an accent.

It's a recommendation, not a request, and it was only that their kids be educated in Russia. Government officials abroad are staying exactly where the fuck they are. If they don't comply, their careers will probably be affected, but it's not an urgent order to leave the US because NUCLEAR WAR IS IMMINENT!!!!!

I tried searching for this story in major Russian outlets but could only find it on that internet-only source. Not in any of the newspapers. It's barely a story. No one cares.

(2) A Putin ally is telling America that there will be NUCLEAR WAR if Trump loses!!!! :stopper:

The guy saying this is Zhirinovsky, who is widely regarded as a giant fucking clown and fascist piece of shit meant to distract the more extreme right wing nationalists so they don't get too rowdy. He is basically the Russian version of Trump. Even 10 years ago, people would roll their eyes and laugh at the mention of his name. He once promised that if he got elected, there'd be free vodka for everyone. He's called for a literal police state, executions, and suspension of elections. Basically, any time anyone wants to freak out about Russia, they just go look for the latest Zhirinovsky quote to convince themselves that NUCLEAR WAR IS IMMINENT!!!!!.
2207
https://mediamatters.org/video/2016/10/12/limbaugh-left-sends-out-rape-police-whenever-theres-sex-no-consent-also-known-rape/213787

Quote
RUSH LIMBAUGH: You know what the magic word, the only thing that matters in American sexual mores today is? One thing. You can do anything, the left will promote and understand and tolerate anything, as long as there is one element. Do you know what it is? Consent. If there is consent on both or all three or all four, however many are involved in the sex act, it's perfectly fine. Whatever it is. But if the left ever senses and smells that there's no consent in part of the equation then here come the rape police. But consent is the magic key to the left.

I love how his "rape police" comment is supposed to describe this metaphorical PC brigade enforcing craaaaazy, wacky leftist ideology when rape is an actual fucking crime that requires the involvement of literal, actual goddamn motherfucking police.

lol :airquote: consent :airquote:
2208
Guys, we all know the police exists to keep the blacks and spics in their place. It's absurd to go after white people for "rape" or "tax evasion" or "securities fraud."
2209
Rasputin polling

That motherfucker just won't die, will he?
2210
538 did a good bit of trolling. hardcore trumpzis are now tweeting that we should repeal the 19th amendment.

Look at how economically disadvantaged they are!
2211
lol, I'm arguing with people who have now shifted into "I'm voting for him for his conservative policies despite not liking his character" tactic. Yes, all of his specific, sane policies that don't change from week to week... :awgee:
why are you arguing with these people?

If you sit through enough hours of lecture and drown in enough material, anything else - anything - seems like a nice break.
2212
lol, I'm arguing with people who have now shifted into "I'm voting for him for his conservative policies despite not liking his character" tactic. Yes, all of his specific, sane policies that don't change from week to week... :awgee:
2213
Former coworker posted that stupid picture with Miley, Beyonce, Kim Kardashian, blahblahblahblah. Someone said, hey, isn't there a difference that they're up there by their own consent instead of being grabbed by a stranger?

Quote
Either way it is vulgar no matter how you look at it. Whether a stranger or them doing it of their own consent.

Ladies, you not wearing enough clothes is just as vulgar as you getting sexually assaulted. You should be ashamed of yourselves.
2214
Hey, look, it's the "FBI: Female Body Inspector" t-shirt morphed into human form!

What a wonderful piece of shit. :awgee:
2215
I was going to bring up opening mayonaisse jars

*laugh track*

Actually, now that I think about it, my cats are good at killing things, so I guess we can get rid of every last one of you.
2216
kill all men

Wait, leave a few to kill cockroaches and other icky bugs for me, pls.
2217
good grief, men are retarded

Welcome to science, cricket.  :smug:

Honestly, though, if I ever run for office, my platform will be to disenfranchise men because seriously how fucking stupid are you guys? All you do is ruin everything.
2219
Speaking of, a reporter is at a Mike Pence event in Iowa.



Quote
an Iowa voter just said to Pence, "If Hillary Clinton gets in, I myself, I'm ready for a revolution because we can't have her in."

Pence then said, "Don't say that."
2220
:smug:

Of course he's a fucking idiot, but it is pretty fucking remarkable to have a sitting US governor flat out say they want an authoritarian president because the Constitution is broken.
2221
teeth, I'ma blow your mind - the fascists have always been here... :ohmy:
2222
Maine governor paul lepage, who is p much trump's mini-me, has now actually said that we need trump to show some "authoritarian power", to save america

https://politicalwire.com/2016/10/11/lepage-suggests-u-s-constitution-broken/

Let's look at that again.

Quote
Sometimes, I wonder that our Constitution is not only broken, but we need a Donald Trump to show some authoritarian power in our country and bring back the rule of law because we've had eight years of a president, he's an autocrat, he just does it on his own, he ignores Congress and every single day, we're slipping into anarchy.

These people are fucking dangerous.
2224
Regardless of the source, he is still literally spreading Russian propaganda.

The Republican candidate for President of the United States in 2016 on the planet Earth is parroting Russian propaganda.
2225
But it'll be great for his ratings once TrumpTV gets off the ground.